Rare commercial opportunity in Shepherdstown offering exceptional visibility, flexibility, and investment potential. Ideally situated directly off Route 45 at a signalized intersection and just minutes from Historic Shepherdstown, this prime corner property benefits from dual access from Martinsburg Pike and Old Martinsburg Road, ensuring convenient ingress and egress. The property features more than 15,000 square feet of commercial space, including a large open-concept area, office space, and two sets of bathrooms. The layout offers potential for multiple tenants with both lower and upper-level spaces, creating an excellent opportunity for owner occupancy or income-producing investment. A substantial parking area accommodates 100+ vehicles, providing ample parking for employees, clients, and visitors. This high-visibility location with strong traffic counts makes it ideal for medical, professional, educational, institutional, or office use. Tenants are responsible for any improvements necessary to customize the space to their business needs. The owner is open to a five-year lease agreement, providing long-term stability for prospective occupants. Located near vibrant downtown Shepherdstown, home to Shepherd University, the area offers an array of restaurants, boutiques, and cultural attractions. Convenient commuter access includes the Shepherdstown MARC train station and proximity to major transportation routes. The property is approximately 50 miles from the Washington, DC Beltway and offers convenient access to Eastern WV Regional Airport, Washington County Regional Airport, Dulles International Airport, Ronald Reagan Washington National Airport, and Baltimore/Washington International Airport.